Impact of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

To evaluate the effect of brimonidine tartrate 0.025% on conjunctival hyperemia in patients treated with netarsudil 0.02%/latanoprost 0.005% mono-therapy for intraocular pressure lowering.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: t
View:

• 1\. Adult patients 18-65 years old diagnosed with open-angle glaucoma or ocular hypertension.

• 2\. Currently on netarsudil 0.02%/latanoprost 0.005% monotherapy for a minimum of 2-6 weeks.

• 3\. Able to move from current topical glaucoma treatment to netarsudil 0.02%/latanoprost 0.005% for a minimum of 4 weeks or longer based on FDA recommended washout per drug classification prior to Visit 3.

• 4\. Experience conjunctival redness as graded on the Efron scale of at least grade 2 after minimum of 4 weeks on netarsudil 0.02%/latanoprost 0.005% mono-therapy or longer based on recommended washout per drug classification 4. Have a best corrected Visual Acuity by Snellen chart of 20/30 or better in study eye.

• 5\. Are willing and able to self-administer or have an able person available to assist with administration of study drug.

⁃ Willing and able to comply with study procedures and attend follow-up visits.

Locations
United States
Missouri
Vision Source
RECRUITING
Kansas City
Contact Information
Primary
Crystal Remington Optometrist, OD
drremington@vseyecare.com
816-531-9100
Time Frame
Start Date: 2025-11-01
Estimated Completion Date: 2027-06-01
Participants
Target number of participants: 35
Treatments
Experimental: Brimonidine Tartrate
Patients experiencing hyperemia greater than grade 2 on Efron scale will receive brimonidine tartrate (Lumify). Photo documentation of hyperemia and patient satisfaction questionnaires will be administered.
Related Therapeutic Areas
Sponsors
Leads: Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,

This content was sourced from clinicaltrials.gov

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