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Performance Evaluation of Dream OCT: AP Study

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

This study will evaluate the clinical performance of a new swept-source OCT imaging device, the VG200D, and to evaluate substantial equivalence with a predicate device, the Cirrus 5000. Clinical performance will be assessed through an agreement and precision analysis of OCT measurement parameters.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 22
Healthy Volunteers: t
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• Subjects 22 years of age or older on the date of informed consent

• Subjects able to understand the written informed consent and willing to participate as evidenced by signing the informed consent

• Subjects with normal eye examinations in both eyes on the date of the study visit as observed with a 90 diopter lens

• BCVA 20/40 or better (each eye) on the date of the study visit

• Subjects 22 years of age or older on the date of informed consent

• Subjects able to understand the written informed consent and willing to participate as evidenced by signing the informed consent

• BCVA 20/40 or better in the study eye

• History of Visual field defects within the previous year from the study visit or measured the day of the study visit consistent with glaucomatous optic nerve damage with at least one of the following two findings:

‣ On pattern deviation (PD), there exists a cluster of 3 or more points in an expected location of the visual field depressed below the 5% level, at least 1 of which is depressed below the 1% level;

⁃ Glaucoma hemi-field test outside normal limits.

• Glaucomatous optic nerve damage as evidenced by any of the following optic disc or retinal nerve fiber layer structural abnormalities:

‣ Diffuse thinning, focal narrowing, or notching of the neuroretinal rim, especially at the inferior or superior poles with or without disc hemorrhage;

⁃ Optic disc neural rim asymmetry of the two eyes consistent with loss of neural tissue

• Subjects 22 years of age or older on the date of informed consent

• Subjects able to understand the written informed consent and willing to participate as evidenced by signing the informed consent

• BCVA 20/400 or better in the study eye

• Diagnosis of some type of retinal pathology by investigator, may include, but not limited to: Macular Degeneration (including patients with drusen and geographic atrophy and choroidal neovascularization), Diabetic Macular Edema, Diabetic Retinopathy, Macular Hole, Epiretinal Membrane, Central Serous Retinopathy, Vein or artery Occlusions and others

• Subjects 22 years of age or older on the date of informed consent

• Subjects able to understand the written informed consent and willing to participate as evidenced by signing the informed consent

• Subjects with one of the following corneal abnormalities:

• i. Cornea disease (e.g., Fuch's or other) ii. Keratoconus iii. Cornea transplant iv. Post refractive surgery (e.g., LASIK or other) v. Dry Eye Syndrome vi. Long-term contact wearers (greater than 1 year)

• BCVA 20/400 or better in the study eye

Locations
United States
Illinois
Illinois College of Optometry
RECRUITING
Chicago
Contact Information
Primary
Mike Sinai, PhD
mike.sinai@intalight.com
6198067636
Time Frame
Start Date: 2025-12-16
Estimated Completion Date: 2026-04
Participants
Target number of participants: 120
Treatments
Normal Healthy Eyes
Eyes without pathology
Glaucoma
Patients with glaucoma in one or both eyes
Retina
Patients with retina pathology in one or both eyes
Cornea
Eyes with cornea abnormality in one or both eyes
Related Therapeutic Areas
Sponsors
Leads: Intalight, Inc
Collaborators: Illinois College of Optometry

This content was sourced from clinicaltrials.gov