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Morphometric Markers of the Effectiveness of Micropulse Cyclophotocoagulation: The Influence of Choroidal Thickness on the Extent and Duration of the Hypotensive Effect

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This prospective study aims to evaluate morphometric markers of treatment response following micropulse transscleral cyclophotocoagulation (MP-CPC) in patients with glaucoma. The study will assess changes in choroidal thickness and the choroidal vascularity index (CVI) measured by optical coherence tomography (OCT) before treatment, 3-7 days after the procedure, and 1 month postoperatively. Intraocular pressure (IOP) will be measured at the same time points. The correlation between changes in choroidal thickness, the choroidal vascularity index (CVI) and IOP reduction will be analyzed. Additionally, the study seeks to determine the minimal baseline choroidal thickness associated with a clinically significant hypotensive effect after MP-CPC.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Decision to treat by MP-CPC Laser

• Patients diagnosed with Glaucoma

• Patients aged 18 years old and above

• Glaucoma that is inadequately controlled on medical therapy

Locations
Other Locations
Kazakhstan
Kazakh Eye Research Institute
RECRUITING
Almaty
Contact Information
Primary
Assiya Shaikenova, MD
shaikenova93@mail.ru
+77055689966
Time Frame
Start Date: 2026-05-18
Estimated Completion Date: 2026-08-18
Participants
Target number of participants: 20
Treatments
Experimental: MicroPulse transscleral cyclophotocoagulation group
Participants in this group will undergo MicroPulse transscleral cyclophotocoagulation for glaucoma. The procedure will be performed using a laser power of 2500 mW, with a treatment duration of 100-120 seconds per hemifield and 5-6 sweeps per hemifield.
Experimental: Conventional transscleral cyclophotocoagulation group
Participants in this group will undergo conventional transscleral cyclophotocoagulation for glaucoma. The procedure will be performed using a laser power of 1.4-2.3 W, with an exposure duration of 1.4-1.8 seconds per coagulation spot.
Related Therapeutic Areas
Sponsors
Leads: Kazakh Eye Research Institute

This content was sourced from clinicaltrials.gov