Medications for Graft Versus Host Disease (GvHD)
These are drugs that have been approved by the US Food and Drug Administration (FDA), meaning they have been determined to be safe and effective for use in Graft Versus Host Disease (GvHD).
Found 5 Approved Drugs for Graft Versus Host Disease (GvHD)
Ruxolitinib
Brand Names
Opzelura, Jakafi
Ruxolitinib
Brand Names
Opzelura, Jakafi
Form: Cream, Tablet
Method of administration: Oral, Topical
FDA approval date: November 16, 2011
Classification: Janus Kinase Inhibitor
Jakafi is a kinase inhibitor indicated for treatment of: intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis in adults.
Orencia
Generic Name
Abatacept
Orencia
Generic Name
Abatacept
Form: Injection
Method of administration: Subcutaneous, Intravenous
FDA approval date: January 01, 2009
Classification: Selective T Cell Costimulation Modulator
ORENCIA is a selective T cell costimulation modulator indicated for: the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA).
Rezurock
Generic Name
Belumosudil
Rezurock
Generic Name
Belumosudil
Form: Tablet
Method of administration: Oral
FDA approval date: July 16, 2021
REZUROCK is indicated for the treatment of adult and pediatric patients 12 years and older with chronic graft-versus-host disease (chronic GVHD) after failure of at least two prior lines of systemic therapy. REZUROCK is a kinase inhibitor indicated for the treatment of adult and pediatric patients 12 years and older with chronic graft-versus-host disease (chronic GVHD) after failure of at least two prior lines of systemic therapy. ( 1 )
Ryoncil
Generic Name
Remestemcel-L-Rknd
Ryoncil
Generic Name
Remestemcel-L-Rknd
Form: Kit
FDA approval date: March 17, 2025
RYONCIL is indicated for the treatment of steroid refractory acute graft versus host disease (SR-aGvHD) in pediatric patients 2 months of age and older. RYONCIL is an allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy indicated for the treatment of steroid-refractory acute graft versus host disease (SR-aGvHD) in pediatric patients 2 months of age and older.
Niktimvo
Generic Name
Axatilimab-Csfr
Niktimvo
Generic Name
Axatilimab-Csfr
Form: Injection
Method of administration: Intravenous
FDA approval date: August 14, 2024
NIKTIMVO is indicated for the treatment of chronic graft-versus-host disease (cGVHD) after failure of at least two prior lines of systemic therapy in adult and pediatric patients weighing at least 40 kg. NIKTIMVO is a colony stimulating factor-1 receptor (CSF-1R)-blocking antibody indicated for the treatment of chronic graft-versus-host disease (cGVHD) after failure of at least two prior lines of systemic therapy in adult and pediatric patients weighing at least 40 kg. ( 1 )
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