Exploratory Study of Early Biomarkers Allowing Dynamic Assessment of Response to Treatment in Cancers of the Head and Neck
Status: Recruiting
Location: See location...
Intervention Type: Genetic
Study Type: Observational
SUMMARY
DART is an exploratory molecular analysis study to assess potential early biomarkers of treatment response in squamous cell carcinoma of the head and neck (HNSCC)
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age 18 years or older
• Patients with histologically confirmed cancer of the head and neck with evidence of recurrent or locally advanced cancer not suitable for treatment with curative intent, or metastatic disease.
• Receiving immunotherapy
• Ability to give informed consent for biological sample collection.
Locations
Other Locations
United Kingdom
The Royal Marsden Hospital
RECRUITING
London
Contact Information
Primary
Ben O'Leary
ben.oleary@icr.ac.uk
02071535337
Time Frame
Start Date: 2022-03-09
Estimated Completion Date: 2026-04
Participants
Target number of participants: 50
Treatments
Patients receiving systemic therapies for cancers of the head and neck
Patients undergoing systemic therapy for recurrent, metastatic, or locally advanced cancer of the head and neck not suitable for treatment with curative intent. A biological research study involving the collection of blood, tumour tissue, saliva, and other body fluids routinely examined during cancer care (e.g. cerebrospinal fluid (CSF), ascites, urine, stool or pleural fluids).
Related Therapeutic Areas
Sponsors
Leads: Royal Marsden NHS Foundation Trust