The RESCUE Study: Survival and Functional Outcomes Following Salvage Surgery for RESidual or reCurrent sqUamous cEll Carcinoma of the Head and Neck

Status: Recruiting
Location: See location...
Intervention Type: Genetic
Study Type: Observational
SUMMARY

The RESCUE study is a combined retrospective and prospective multicentre cohort study investigating the survival and functional outcomes in patients undergoing salvage surgery for recurrent, residual, and new primary head and neck squamous cell carcinoma (SCC). Additionally, the RESCUE study will contain an exploratory molecular analysis of consenting patients to assess the relationship between cancer genomics, previous radiotherapy, and recurrence in head and neck cancer.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Aged over 18

• Previous H\&N SCC treated with radiotherapy with or without chemotherapy

• Local or regionally recurrent, residual, or new primary SCC of the oropharynx, oral cavity, larynx, and hypopharynx

• Ability to give informed consent for biological sample collection (molecular analysis study only)

Locations
Other Locations
United Kingdom
Head and Neck Unit, Royal Marsden Hospital
RECRUITING
London
Contact Information
Primary
Andrew Williamson
andrew.williamson2@rmh.nhs.uk
02073528171
Backup
Jeane Guevara
RESCUE@rmh.nhs.uk
02073528171
Time Frame
Start Date: 2023-09-08
Estimated Completion Date: 2029-04-01
Participants
Target number of participants: 400
Treatments
Group 1
Participants with previous diagnosis of H\&N SCC treated with radiotherapy. Recurrent, residual, or new primary SCC of the oropharynx, oral cavity, larynx, and hypopharynx treated with salvage surgery
Sponsors
Leads: Royal Marsden NHS Foundation Trust

This content was sourced from clinicaltrials.gov