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Prospective Exploratory Study on rTMS for Migraine Under the Guidance of MEG

Status: Recruiting
Location: See location...
Intervention Type: Device, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Using magnetoencephalography to locate and regulate targets in migraine patients, repeating transcranial magnetic stimulation to physically regulate targets, and evaluating the safety and effectiveness of this treatment method through headache related scales. Using whole genome data and scale scores for correlation analysis, and conducting randomized controls with traditional drugs to explore new approaches for migraine.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 15
Maximum Age: 50
Healthy Volunteers: f
View:

• Complies with specific disease diagnosis: A. Headaches that meet the criteria of B and C (headaches that meet the characteristics of tension headaches or migraines) should occur at least 15 days per month and last for at least 3 months; B. Headaches that meet the criteria of 1.1 migraine without aura diagnosis B-D or 1.2 migraine with aura B and C occurring at least 5 times; C. Headache meets any of the following criteria and occurs for more than 8 days per month, lasting for more than 3 months: ①1.1 C and D of migraine without aura②1.2 B and C of migraine with aura③ The migraine attack perceived by the patient can be relieved by taking triptan or ergot, which cannot be better explained by other diagnoses in ICHD-3.

• Must be able to swallow tablets

• Signed and dated informed consent form Promise to comply with research procedures and cooperate in implementing the entire research process

Locations
Other Locations
China
Ruijin Hospital
RECRUITING
Shanghai
Contact Information
Primary
Xiaodan Wang, Doctor
wxd12466@rjh.com.cn
+86-21-64370045
Time Frame
Start Date: 2025-02-06
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 60
Treatments
Experimental: RTMS intervention group
(1) The patient undergoes pseudo stimulus intervention in the first week and real stimulus intervention afterwards, which is blind to the patient. (2) Starting from the second week, true stimulation intervention will be conducted for 4 weeks, with each patient making an appointment for 1 month.
Other: Sibelium treatment group
Patients were evaluated and followed up with a scale based on medication intervention.
Related Therapeutic Areas
Sponsors
Leads: Ruijin Hospital

This content was sourced from clinicaltrials.gov