Role of Selective Attention for Sound Modulations in the Listening Effort of Patients With Cochlear Implants

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Cochlear implant users perceive mainly sound amplitude modulation cues. Processing of these amplitude modulations can be subject to interferences, so that the perception of a modulation in a target sound can be impaired by a superimposed sound if this sound contains a similar modulation. Such phenomenon, which is observed both in subjects with normal-hearing and in cochlear-implant users, could be explained by difficulties to direct attention to relevant information in complex sound signals. Selective auditory attention also plays a crucial role in speech comprehension in cocktail-party situations where the speech of multiple talkers get mixed at the ear of a listener. Cochlear implant users typically struggle in these cocktail-party situations and report intense listening effort. The present clinical trial aims at evaluating the contribution of selective auditory attention for sound modulations to the listening effort of patients with cochlear implants and of healthy volunteers with normal-hearing during speech perception under cocktail-party-like conditions. Selective auditory attention abilities of patients and controls will be assessed using a psychoacoustical test whereby their ability to detect a target sound amplitude modulation will be measured both in the absence and in the presence of an interfering (i.e. distracting) amplitude modulation occurring in a distant spectral region from that of the target. The effect of this distractor's presence on modulation detection performance will serve as a behavioural index of the subject's auditory attention capacities. The attentional capacity index will then be tested as a predicting factor for the listening effort of the subject during a speech-in-noise consonant identification task. Listening effort will be measured from the pupil dilation response to the presented speech units (pseudowords). This study will enhance our understanding of cochlear implant user's perception and listening effort and will serve as a basis for prognostic tests of listening effort and of implantation success for cochlear implant candidates, based on a simple measurement of auditory attentional abilities.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:

⁃ Arm 1: patient with Cochlear Implant

• Having a unilateral Oticon Medical cochlear implant

• Duration of use of the implant of 6 months or more

• Disyllabic word recognition score of at least 40% on average in silence, to limit floor effects in hearing tests.

• Disyllabic word recognition score not exceeding 30% on the contra-lateral ear alone, aided or not, in silence.

⁃ Arm 2: volunteers with normal hearing

⁃ \- Normal tonal audiometry for the age

⁃ For both

• Age between 18 and 80 years old

• Mother tongue : French

• Normal vision with or without correction

• Absence of eye pathologies (cataracts, nystagmus, amblyopia, macular degeneration).

• Not taking psychotropic drugs or drugs affecting the parasympathetic nervous system

• Absence of pathology or neurological history (especially head trauma, stroke).

• Information and signing of a consent prior to any act related to research

Locations
Other Locations
France
Assistance Publique-Hôpitaux de Paris
RECRUITING
Paris
Contact Information
Primary
Isabelle MOSNIER, MD
isabelle.mosnier@aphp.fr
+33 1 42 16 26 06
Backup
Dorothée ARZOUNIAN, Ph. D
dorothée.arzounian@ens.fr
Time Frame
Start Date: 2021-12-08
Estimated Completion Date: 2026-02-22
Participants
Target number of participants: 170
Treatments
Experimental: Patients with cochlear implant
Patients with cochlear implant for 6 months and more
Active_comparator: Healthy volunteers (normal hearing)
Healthy volunteers with a normal tonal audiometry for age
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov