Impact of Severe to Profound Deafness on Cognitive Functions in Middle-aged Adults
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years. The aim of our study was to compare cognitive function between patients with severe and profound hearing loss and patients with normal hearing in patients aged 45 to 64 years.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Maximum Age: 64
Healthy Volunteers: t
View:
• Cases: Patients aged between 45 to 64 years with severe to profound bilateral post-lingual sensorineural hearing loss with a maximum intelligibility of 70% (disyllabic words) in free-field silence with hearing aids at 60 dB SPL, current in french
• Controls: normal hearing subjects matched on age, sex and education level
Locations
Other Locations
France
Centre de Recherche en Audiologie (CReA) - Groupe Hospitalier Pitié-Salpêtrière
RECRUITING
Paris
Contact Information
Primary
Isabelle Dr MOSNIER, MD
isabelle.mosnier@aphp.fr
142162612
Backup
Nassima SCHMOLL
nassima.schmoll@aphp.fr
142163089
Time Frame
Start Date: 2022-05-24
Estimated Completion Date: 2027-05-24
Participants
Target number of participants: 180
Treatments
Experimental: Cases: Patients with severe to profound hearing loss
Patients aged between 45 to 64 years with severe to profound bilateral post-lingual sensorineural hearing loss with a maximum intelligibility of 70% (disyllabic words) in free-field silence with hearing aids at 60 dB SPL
Active_comparator: Controls: 90 matched subjects with normal hearing
Healthy controls aged between 45 to 64 years with normal hearing on pure-tone audiometry (as function of ISO 7029 reference)
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris