A Post-approval, Prospective, Nonrandomized, Single-arm Multicenter Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

Status: Recruiting
Location: See all (8) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of the study is to assess the continued efficacy and safety of cochlear implantation in participants aged 5 years and above with Unilateral Hearing Loss (UHL)/Single Sided Deafness (SSD) supporting a change indication for use.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Healthy Volunteers: f
View:

⁃ • Individuals 18 years or older (Group A)

⁃ Ear to be Implanted:

⁃ Severe sensorineural hearing loss (HL) defined as: Pure-tone average at 0.5, 1, 2, 4 kHz \>80 dB HL ; Aided Consonant-Nucleus-Consonant Test (CNC) score ≤5% and

⁃ Normal Hearing Ear:

⁃ Normal or near normal hearing defined as an average of (0.5, 1, 2, 4kHz) ≤ 30 dB HL

⁃ • Children 5 years to 17 years, 11 months (Group B)

⁃ Ear to be Implanted:

⁃ Severe sensorineural HL defined as: Pure-tone average at 0.5, 1, 2, 4 kHz \>80 dB HL; Aided CNC score ≤5% and

⁃ Normal Hearing Ear:

⁃ Normal or near normal hearing defined as an average of (0.5, 1, 2, 4kHz) ≤ 30 dB HL

• Previous experience with a current conventional treatment option for unilateral \[SSD\] HL (HA, bone-conduction device, or CROS technology), if no previous experience a minimum trial period of two weeks is required

• English spoken as a primary language

• Willing and able to provide written informed consent

Locations
United States
California
Stanford University
RECRUITING
Palo Alto
Colorado
Rocky Mountain Ear Center
RECRUITING
Englewood
Iowa
University of Iowa
RECRUITING
Iowa City
North Carolina
University of North Carolina
RECRUITING
Chapel Hill
New York
New York Eye and Ear Infirmary
RECRUITING
New York
Ohio
Nationwide Children's Hospital
WITHDRAWN
Columbus
Texas
University of Texas Southwestern Medical Center- Department of Otolaryngology Head and Neck Surgery
WITHDRAWN
Dallas
Washington
Virginia Mason Medical Center
RECRUITING
Seattle
Contact Information
Primary
PRS Specialist
cltd-prs-admin@cochlear.com
+612294286555
Time Frame
Start Date: 2022-08-19
Estimated Completion Date: 2027-06
Participants
Target number of participants: 60
Treatments
Other: Children and adults with unilateral hearing loss/single-sided deafness
Authors
Ursula Findlen
Related Therapeutic Areas
Sponsors
Leads: Cochlear
Collaborators: NAMSA

This content was sourced from clinicaltrials.gov