Neural Prediction to Enhance Language Outcomes in Children With Cochlear Implant

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The language outcome of children receiving cochlear implantation to address bilateral sensorineural hearing loss is more variable than that of typical hearing children. The research is focused upon development of neural predictive models based upon brain imaging to forecast language after cochlear implantation on the individual child level. The long-term goal is improving children's language by using predictive models to enable a custom predict to prescribe approach to intervene with more effective behavioral therapy for children at risk to develop poorer language. The investigators previously developed models for short term language outcome of English-learning implanted children. The aims of this study are to 1. Develop models able to predict long term outcome for English- learning and Spanish-learning children; and 2. To evaluate whether English-learning children predicted to achieve lower language based on the investigators' previously constructed models can demonstrate significant gains from Parent Implemented Communication Treatment (PICT). PICT is an intensive parent education program about strategies to improve children's communication.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 5
Healthy Volunteers: f
View:

• Children with sensorineural hearing loss who meet clinical criteria for cochlear implantation in both ears who meet the following age criteria at time cochlear implant evaluation begins:

‣ Age 5 years and under.

⁃ English or Spanish as the dominant language.

• English or Spanish dominant language in the home.

• Children with bilateral sensorineural hearing loss who meet clinical criterial for cochlear implantation

• English dominant spoken language by family

• Age at implantation of 36 months and younger when treatment begins

• Parent or caregiver that is willing to participate who understands spoken English

• Child is exposed to spoken language by at least one parent (total communication or auditory/oral) in the home

Locations
United States
Illinois
Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITING
Chicago
Contact Information
Primary
Nancy M Young, MD
nyoung@luriechildrens.org
312-227-6812
Backup
Emily (Shimeng) Xu, PhD
sxu@luriechildrens.org
Time Frame
Start Date: 2023-01-23
Estimated Completion Date: 2028-01-23
Participants
Target number of participants: 700
Treatments
No_intervention: Non-treatment Model Building
Experimental: Communication Treatment
Related Therapeutic Areas
Sponsors
Collaborators: University of Southern California, Northwestern University, University of Miami, The University of Texas at Dallas, Chinese University of Hong Kong, University of North Carolina, Chapel Hill
Leads: Ann & Robert H Lurie Children's Hospital of Chicago

This content was sourced from clinicaltrials.gov

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