BurdEn of NEw Onset Atrial FIbrillation in patienTs With Acute Myocardial Infarction: the BENEFIT-AMI Multicenter Prospective Registry
Status: Recruiting
Location: See all (5) locations...
Intervention Type: Device
Study Type: Observational
SUMMARY
To validate the prognostic importance of the burden of new-onset atrial fibrillation (NOAF) complicating acute myocardial infarction (AMI) in a prospectively designed hospital-based registry. To characterize those factors that contribute to the progression of post-MI NOAF burden. To establish a prediction model for the risk stratification of patients with NOAF complicating AMI. To explore the clinical usefulness of NOAF burden in guiding the anticoagulation therapy among patients with post-MI NOAF.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:
• Adult patients (\>18 years old);
• Patient with AMI (including STEMI and NSTEMI) who developed NOAF during the index hospitalization;
• Patients must have received in-hospital CEM for at least 5 days;
• Patients must give informed consent.
Locations
Other Locations
China
Kaifeng Central Hospital
RECRUITING
Kaifeng
Luoyang Central Hospital
RECRUITING
Luoyang
Department of Cardiology, Shanghai Tenth People's Hospital
RECRUITING
Shanghai
Shanghai Seventh People's Hospital
RECRUITING
Shanghai
The First Affiliated Hospital of Zhengzhou University
RECRUITING
Zhengzhou
Contact Information
Primary
Jiachen Luo, M.D., Ph.D.
messichen@tongji.edu.cn
+86-188-0179-0469
Time Frame
Start Date: 2020-10-01
Estimated Completion Date: 2028-06-30
Participants
Target number of participants: 774
Treatments
Low burden of new-onset atrial fibrillation
Patients with MI who are free from a medical history of atrial fibrillation (AF) will be recognized as NOAF if they develop an atrial fibrillation (lasting for at least 30 seconds which are recorded by CEM) incident during hospitalization. Among this subset of patients, those who have a NOAF burden value\<10.87% (previously established) will be divided into the low burden group.
High burden of new-onset atrial fibrillation
For patients with NOAF complicating AMI, those who have a NOAF burden value≥10.87% (previously established) will be divided into the high burden group.
Authors
Related Therapeutic Areas
Sponsors
Leads: Shanghai 10th People's Hospital
Collaborators: The First Affiliated Hospital of Zhengzhou University, Kaifeng Central Hospital, Shanghai 7th People's Hospital, Luoyang Central Hospital, Shanghai Tong Ren Hospital