The STEMI Optimization Trial - Ischemic Postconditioning (DANAMI4-iPOST) and Intravascular Ultrasound Guided PCI in STEMI (DANAMI4-iSTEMI)
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of is study is to investigate whether ischemic postconditioning (iPOST) and intravascular ultrasound-guided (IVUS) percutaneous coronary intervention (PCI) improve the clinical outcome of patients with ST-segment elevation myocardial infarction treated with primary PCI.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥18 years
• Acute onset of chest pain with \<12 hours duration
• STEMI as characterized by 2 mm ST elevation in 2 or more V1 through V4 leads or presumed new left bundle branch block with minimum of 1 mm concordant ST elevation or 1 mV ST-segment elevation in the limb lead (II, III and aVF, I, aVL) and V4-V6 or ST depression in 2 or more V1 through V4 leads indicating posterior AMI.
Locations
Other Locations
Denmark
Heart Center, Rigshospitalet
RECRUITING
Copenhagen
Contact Information
Primary
Thomas Engstrøm, MD PhD DSci
Thomas.Engstroem@regionh.dk
+45 3545 8444
Backup
Jacob Lønborg, MD PhD DMSci
jacob.thomsen.loenborg01@regionh.dk
+45 3545 8176
Time Frame
Start Date: 2021-04-01
Estimated Completion Date: 2031-02-01
Participants
Target number of participants: 2500
Treatments
Active_comparator: PCI standard
Experimental: PCI standard + ischemic conditioning
Experimental: Stent with ultrasound
Active_comparator: Stent without ultrasound
Related Therapeutic Areas
Sponsors
Leads: Thomas Engstrom