Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients With MINOCA
Myocardial infarction with non-obstructive coronary arteries (MINOCA) (i.e.\<50% stenoses) on coronary angiography) is an underappreciated clinical entity concerning 5-6% of patients with acute myocardial infarction. Approximately 50% of these patients remain without appropriate diagnosis and treatment. The MINOCA study aims at systematically assessing the frequency of underlying pathologies of MINOCA and outcomes with a multidisciplinary etiologic work-up and follow-up of 5 years including, for the first time, an implantable cardiac monitor (ICM) to assess the frequency of atrial fibrillation as underlying cause for MINOCA.
• ≥18 years of age
• Written informed consent
• Acute myocardial infarction (AMI) type 1 in accordance with the 4th universal definition of myocardial infarction
• Non-obstructive coronary arteries on angiography defined as the absence of coronary artery stenoses ≥50% in any potential infarct-related artery
• No clinically overt specific cause for the acute presentation
• Subendocardial or transmural late gadolinum enhancement (LGE) consistent with an ischemic etiology on cardiac magnetic resonance imaging (CMR)
• No clear underlying cause of MINOCA and therefore increased probability of atrial fibrillation
• ≥18 years of age
• Written informed consent
• AMI type 1 in accordance with the 4th universal definition of myocardial infarction
• Non-obstructive coronary arteries on angiography defined as the absence of coronary artery stenoses ≥50% in any potential infarct-related artery
• No clinically overt specific cause for the acute presentation
• Subendocardial or transmural LGE consistent with an ischemic etiology on CMR