Cellular precOnditioning for Post-Surgical Myocardial Ischemic Complications - Observational Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to collect health data on people who are at high risk of having heart complications and are having a surgery that is not on the heart. The main questions it aims to answer are: * Is this study feasible in terms of recruiting enough people to participate in this study? * How often do heart complications happen in people who are at high risk of heart complications and are having a surgery that is not on the heart? Participants will have their usual care and will also be asked to: * Have extra bloodwork done * Complete some surveys * Have two echocardiograms (ultrasounds of the heart) * Continue to follow-up with the research team for one year after their surgery Researchers will compare how often heart complications occur in this high risk population to a future study where participants will receive stem cells before their surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Healthy Volunteers: f
View:

⁃ A participant must meet all 5 inclusion criteria to be eligible:

• Referred for elective intermediate to high risk noncardiac surgery as defined by the American Heart Association guidelines (e.g., intrathoracic, open intraabdominal, or open vascular surgery)

• 45 years of age or older

• Revised cardiac risk index ≥ 2

• NT-proBNP level of ≥ 200 pg/mL

• Able to provide informed consent

Locations
Other Locations
Canada
The Ottawa Hospital
RECRUITING
Ottawa
Contact Information
Primary
Meredith Conboy, MSc
mconboy@ohri.ca
613-737-8899
Backup
Manoj M Lalu, MD, PhD
mlalu@toh.ca
613-737-8899
Time Frame
Start Date: 2023-02-15
Estimated Completion Date: 2025-09
Participants
Target number of participants: 12
Related Therapeutic Areas
Sponsors
Collaborators: Canadian Anesthesiologists' Society, The Ottawa Hospital Academic Medical Association
Leads: Ottawa Hospital Research Institute

This content was sourced from clinicaltrials.gov