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Effect of a Vegetarian Diet on Innate Immunity in Patients With Myocardial Infarction and in Healthy Volunteers (FRESH-MI Study)

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to assess the effect of a vegetarian diet on innate immunity of patients with a recent acute myocardial infarction and healthy participants. Also, we will assess the willingness to adapt a more vegetarian eating habit. Study subjects will follow a vegetarian diet for five weeks, whereafter a stabilisation period of six weeks will follow. Then, participants will follow to the other dietary intervention for five weeks. Blood will be drawn at given time points to analyse inflammatory parameters.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Acute myocardial infarction (STEMI/NSTEMI) with a clear culprit lesion on angiography and successful primary percutaneous coronary intervention (PCI) \<1 week before randomisation

• Body mass index between 18.5 and 35 kg/m2

• Written informed consent

• Body mass index between 18.5 and 35 kg/m2

• Written informed consent

Locations
Other Locations
Netherlands
Radboudumc
RECRUITING
Nijmegen
Contact Information
Primary
Robin Nijveldt, MD, PhD
robin.nijveldt@radboudumc.nl
0031243616785
Backup
Saloua El Messaoudi, MD, PhD
Saloua.ElMessaoudi@radboudumc.nl
0031243616785
Time Frame
Start Date: 2024-01-26
Estimated Completion Date: 2027-09-01
Participants
Target number of participants: 120
Treatments
Experimental: Vegetarian diet
Vegetarian diet during five weeks
No_intervention: No change diet
The 'habitual' diet during five weeks. There are no specific restrictions to their diet.
Related Therapeutic Areas
Sponsors
Leads: Radboud University Medical Center

This content was sourced from clinicaltrials.gov