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Efficacy of the Pressure Optimization Protocol (POP )Versus Conventional Stent Deployment Strategy During Primary Percutaneous Coronary Intervention.

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Efficacy of the Pressure Optimization Protocol (POP) versus Conventional Stent Deployment Strategy during Primary PCI: An Open Label Randomized Clinical Trial The investigators will compare conventional rapid stent inflation/deflation during primary PCI with higher pressure and prolonged duration of stent deployment Study Hypothesis: The POP in stent deployment is superior to the conventional stent deployment approach with a significantly higher achievement of the TIMI III flow, significantly lesser occurrence of slow flow/no-reflow, and significantly higher rate of ST-Segment resolution during primary PCI.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients aged 18 years and above.

• Patients undergoing primary percutaneous coronary intervention (PCI) with stent implantation.

• Presence of significant coronary artery stenosis (greater than 70% diameter reduction) confirmed by angiography.

Locations
Other Locations
Pakistan
National institute of cardiovascular diseases
RECRUITING
Karachi
Contact Information
Primary
Abdul Hakeem, professor
abdulhakeem@gmail.com
+923355554342
Backup
Shakir Zada, fellow
dr.shakir637@gmail.com
+923469467449
Time Frame
Start Date: 2024-05-15
Estimated Completion Date: 2024-11
Participants
Target number of participants: 400
Treatments
Other: POP Protocol
Patients in this arm will be treated according to the POP protocol for stent deployment
Other: Conventional method
Patients in this arm will be treated with conventional method (rapid inflation-deflation protocol) for stent deployment
Sponsors
Leads: National Institute of Cardiovascular Diseases, Pakistan

This content was sourced from clinicaltrials.gov