STunning in Acute Myocardial Infarction - Beta Blockers, Angiotensin Converting Enzyme Inhibitors and Sodium/Glucose Cotransporter 2 Inhibitors Trial A Low Intervention Clinical Tria
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The objective of this trial is to examine the effect of immediate versus late administration of beta blockers, angiotensin converting enzyme inhibitors (ACEI), and sodium/glucose cotransporter 2 (SGLT2) inhibitors on echocardiographic parameters and biomarkers in subjects with ST-elevation myocardial infarction (STEMI)
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients with STEMI who undergo primary PCI within 6 hours of symptom onset (Excluding prodromal symptoms)
• Informed consent
Locations
Other Locations
Sweden
Sahlgrenska University Hospital
RECRUITING
Gothenburg
Contact Information
Primary
Björn Redfors, Professor
bjoern.redfors@wlab.gu.se
+46 31342100
Backup
Margareta Scharin Täng, PhD
margareta.scharin.tang@vgregion.se
0736916467
Time Frame
Start Date: 2025-01-06
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 120
Treatments
Active_comparator: Bisoprolol
Bisoprolol within 24 hours of PCI
No_intervention: No Bisoprolol
no beta blocker until day 7±12 hours
Active_comparator: Ramipril
Ramipril within 24 hours of PCI
No_intervention: No Ramipril
no ramipril until day 7±12 hours after PCI
Active_comparator: Dapagliflozin
Dapagliflozin within 24 hours versus
No_intervention: No Dapagliflozin
no dapagliflozin treatment until day 7±12 hours after PCI
Related Therapeutic Areas
Sponsors
Leads: Vastra Gotaland Region