Oral Health Intervention Study in Patients with Myocardial Infarction and Periodontal Disease: a Simulated RCT Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of this study is to establish a shared database of acute myocardial infarction patients with periodontitis, to clarify the clinical benefits of periodontitis intervention on acute myocardial infarction patients through simulated RCT study, and to establish a high-level database of acute myocardial infarction patients with periodontitis, so as to promote the application of oral health intervention in clinical practice.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Healthy Volunteers: f
View:

• 1)Patients diagnosed with ST-segment elevation myocardial infarction (STEMI). 2)Patients with severe periodontal disease, defined as:

⁃ 5 teeth with clinical attachment loss (CAL) ≥ 4 mm.

‣ Subgingival probing depth (PD) ≥ 6 mm. ③≥ 8 teeth with gingival bleeding on probing (BOP). 3)Age ≥30 years. 4)Written informed consent provided.

Locations
Other Locations
China
Shanghai Tenth People's Hospital
RECRUITING
Shanghai
Contact Information
Primary
Jiawen Wu
chloewuu@foxmail.com
86+17717070557
Time Frame
Start Date: 2020-12-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 100
Treatments
Experimental: Periodontal Health Intervention Group
Participants in this arm will receive comprehensive periodontal health interventions, including:~1. Full periodontal evaluation using dental mirrors and probes (assessing visible plaque, probing depth, bleeding on probing, and attachment loss).~2. Supragingival scaling, root planing, and professional plaque removal.~3. Temporary restoration of carious lesions and extraction of root remnants, as needed.~4. Personalized oral hygiene instruction, including the use of multi-tufted brushes, toothpaste, floss, and interdental brushes.
No_intervention: Standard Care Group
Participants in this arm will receive standard care without specific periodontal interventions. This includes routine medical management for myocardial infarction, as per standard clinical guidelines, without structured periodontal treatment.
Related Therapeutic Areas
Sponsors
Leads: Shanghai 10th People's Hospital

This content was sourced from clinicaltrials.gov