Assessment of Myocardial Fibrosis by 18F-FAPI/PET-CT in Patients With Myocardial Infarction-associated Ventricular Aneurysm
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The study will use 18F-FAPI PET/CT to study myocardial fibrosis in patients diagnosed with myocardial infarction-associated ventricular aneurysm (MI-VA). Participants will receive the PET/CT scan during hospital stay, as well as serial echocardiography and telephonic follow-ups. Analysed will focus on the characterization of myocardial fibrosis and its correlations with the clinical prognosis in the patients.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
View:
• Aged 18-75 years old
• Diagnosed with STEMI or NSTEMI (ACC/AHA guidelines)
• Half male and half female
• Undergo CAG and PCI treatment;
• Receive either echocardiography or CMR to identify a ventricular aneurysm;
• Written informed consent
Locations
Other Locations
China
Renji Hospital
RECRUITING
Shanghai
Contact Information
Primary
ZHIGUO ZOU, MD, PhD
zouzhiguo@renji.com
13524596108
Time Frame
Start Date: 2024-11-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 20
Treatments
Acute myocardial infarction-associated ventricular aneurysm
Participants in this group are patients diagnosed with a ventricular aneurysm secondary to acute myocardial infarction (AMI). Diagnosis of AMI is based on clinical presentation, elevated cardiac biomarkers, ECG changes, and coronary angiogram. Ventricular aneurysm is mainly diagnosed by imaging modalities such as echocardiography and cardiovascular magnetic resonance (CMR).
Acute myocardial infarction without evidence of ventricular aneurysm
Participants in this group are patients diagnosed with AMI only. Diagnosis of AMI is based on clinical presentation, elevated cardiac biomarkers, ECG changes, and coronary angiogram. Echocardiography or CMR does not identify a ventricular aneurysm.
Related Therapeutic Areas
Sponsors
Leads: RenJi Hospital