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Routine Use of Potassium Competitive Acid Blocker Versus Guideline-Directed Gastrointestinal Protection Strategy in Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention on Dual Antiplatelet Therapy: A Randomized Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This study aims to compare the clinical outcomes between routine use of potassium competitive acid blocker (P-CAB) and guideline-directed gastrointestinal (GI) protection strategy in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) and being treated with dual antiplatelet therapy (DAPT).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Healthy Volunteers: f
View:

• Patients aged 19 years or older.

• Patients diagnosed with acute myocardial infarction (ST-segment elevation myocardial infarction \[STEMI\] or non-ST-segment elevation myocardial infarction \[NSTEMI\]).

• Patients who underwent percutaneous coronary intervention (PCI) with drug-eluting stents (DES) or drug-coated balloons (DCB).

• Patients (or their legal representatives) who understood the study risks and benefits and provided voluntary written informed consent.

Locations
Other Locations
Republic of Korea
Samsung Medical center
RECRUITING
Seoul
Time Frame
Start Date: 2026-06-23
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 5000
Treatments
Experimental: Routine Potassium Competitive Acid Blocker Group
Active_comparator: Guideline-Directed Gastrointestinal Protection Group
Sponsors
Leads: Samsung Medical Center

This content was sourced from clinicaltrials.gov