Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes Mellitus Undergoing Coronary Revascularisation

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Patients living with diabetes mellitus have double the risk of kidney failure compared to patients without diabetes following use of dye in many x-rays and procedures to diagnose and treat narrowing of the arteries (blood vessels) in the heart that can lead to angina or a heart attack. Heart disease is the commonest cause of death in patients with diabetes. People with diabetes are more likely to need these tests/treatments. By identifying those at greater risk of kidney complications we may be able to make these tests/treatments safer and offer them to more patients with diabetes.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age \> 18 years, known diabetes mellitus or BM on arrival consistent with probable diagnosis of diabetes, eGFR \<60 ml/min

• Undergoing a PCI procedure

• Agrees to the additional collection of blood and urine samples as outlined above

• Agrees to access of their clinical records for the collection of relevant medical data

• No history or signs of drug abuse

• Able to understand and sign the written Informed Consent Form

• Able and willing to follow the Protocol requirements

Locations
Other Locations
United Kingdom
The London Chest Hospital
RECRUITING
London
Contact Information
Primary
AKHIL KAPUR
akhil.kapur@bartsandthelondon.nhs.uk
0208 983 2413
Backup
KATIE QURESHI
katie.qureshi@bartsandthelondon.nhs.uk
0208 983 2477
Time Frame
Start Date: 2009-06-24
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 250
Treatments
Diabetes mellitus, renal impairment
Patients with both diabetes mellitus and eGFR \<60 ml/min
Related Therapeutic Areas
Sponsors
Leads: Barts & The London NHS Trust

This content was sourced from clinicaltrials.gov