Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease, Effects of Mechanical Unloading on Myocardial Function and Structure in Humans

Status: Recruiting
Location: See all (3) locations...
Study Type: Observational
SUMMARY

Design: This is a registry project; there are no investigational treatments, drug or procedures associated with participation in registry activities. This project is an organized functional data and tissue data gathering and storing (database) endeavor with specific focus on the functional, structural, and molecular aspects of heart failure. Data collection will not immediately influence the course of treatment for any patient.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 13
Healthy Volunteers: f
View:

• \>18 years of age diagnosed with heart failure undergoing either LVAD implantation or heart transplantation

• 13 to 18 years of age, specifically, older children with heart failure whose body mass index is large enough to accommodate and LVAD

Locations
United States
Utah
Intermountain Medical Center
RECRUITING
Murray
University of Utah Health Sciences Center
RECRUITING
Salt Lake City
VA Salt Lake City Health Care System
RECRUITING
Salt Lake City
Contact Information
Primary
John Kirk
john.kirk@hsc.utah.edu
801-585-2944
Backup
Stavros Drakos, M.D., Ph.D.
stavros.drakos@hsc.utah.edu
801-585-2340
Time Frame
Start Date: 2008-09
Estimated Completion Date: 2028-01
Participants
Target number of participants: 300
Treatments
Advanced Heart Failure Therapy Group
Patients diagnosed with end stage heart failure undergoing either VAD implantation or heart transplantation.
Normal Hearts Group
Control samples will be obtained from individuals undergoing other types of cardiac surgery during which it is routine to discard some tissue intraoperatively.
Authors
Josef Stehlik
Related Therapeutic Areas
Sponsors
Leads: University of Utah
Collaborators: Hunter Holmes McGuire VA Medical Center, Intermountain Health Care, Inc., VA Salt Lake City Health Care System

This content was sourced from clinicaltrials.gov