Lymphatic System Stimulation and Fluid Overload Symptoms in Patients With Heart Failure

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this pilot clinical trial is to obtain preliminary data on the effects of lymphatic exercise training in patients with heart failure. The main question\[s\] it aims to answer are: 1. Does performing lymphatic exercise decrease fluid overload symptoms (shortness of breath, lower legs swelling, fatigue), thoracic fluid content, and body fluid level? 2. Does performing lymphatic exercise improve sleep and quality of life (QOL)? Participants with heart failure will be randomly assigned into two groups: Group 1 will receive training on lymphatic exercises, and will perform these training for 4 weeks. This group will also be trained to monitor daily their weight, heart rate and blood pressure, and fluid overload symptoms. Group 2 will be trained to daily monitor their weight, heart rate and blood pressure, and fluid overload symptoms. This group will not perform the lymphatic exercises. Researchers will compare the two groups at the baseline and after delivering the 4 week-interventions to see 1. if lymphatic exercise helped decrease symptoms associated with fluid overload like shortness of breath, lower leg swelling, and fatigue. 2. if lymphatic exercises decreased thoracic fluid content and total body fluid level . 3. if the lymphatic exercise helped improve sleep and quality of life (QOL).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Clinical diagnosis of HF with New York Heart Association (NYHA) functional class II, III, or IV

• Willing and able to complete the home-based TOLF program upon discharge from the hospital to home

Locations
United States
New Jersey
Cooper University Health Care (Cooper)
RECRUITING
Camden
Contact Information
Primary
Rida Gharzeddine, PhD
rg1041@rutgers.edu
2016570912
Backup
Elizabeth Cerceo, MD
cerceo-elizabeth@cooperhealth.edu
856-577-8975
Time Frame
Start Date: 2023-06-15
Estimated Completion Date: 2025-10
Participants
Target number of participants: 80
Treatments
Experimental: The Optimal Lymph Flow (TOLF)
Participants in this arm perform lymphatic exercise training AND daily monitoring of fluid overload symptoms for 4 weeks
Active_comparator: Daily Monitoring
Participants in this arm will only perform daily monitoring of fluid overload symptoms including weight, heart rate, and blood pressure for 4 weeks. Participants will NOT perform TOLF in this arm.
Related Therapeutic Areas
Sponsors
Leads: Rutgers, The State University of New Jersey
Collaborators: The Cooper Health System

This content was sourced from clinicaltrials.gov