Comparison of Cardiac Resynchronisation Therapy (CRT) Response Using High Frequency (HF) - ECG or Q-LV Guided Optimisation for Left Ventricular, Pacing Site
Status: Unknown
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The research aims to compare the response of Cardiac Resynchronisation Therapy (CRT) using HF ECG guided or the conventional method of Q-LV measurement guided optimisation for left ventricular, pacing site.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:
• • Eligible for implantation of a CRT-D device according to published relevant ESC and CCS guidelines;
‣ In sinus rhythm;
⁃ NYHA class II, III or IV
⁃ Have reviewed, signed and dated an informed consent.
⁃ Age 18
Locations
Other Locations
United Kingdom
University Hospitals Birmingham
RECRUITING
Birmingham
Contact Information
Primary
Jamie Walton, Bsc
jamie.walton@uhb.nhs.uk
01213712535
Backup
Francisco Leyva-Leon, MD
francisco.leyva@uhb.nhs.uk
01213712500
Time Frame
Start Date: 2023-10-31
Completion Date: 2025-07
Participants
Target number of participants: 180
Treatments
Experimental: HF-ECG guided LV pacing site optimisation
Participants will have the left ventricular pacing site programmed based on the results of HF-ECG mapping to locate the area of latest activation and best pattern of paced resynchronisation.
Active_comparator: Q-LV guided LV pacing site optimisation
Participants will have the left ventricular pacing site programmed based on the results of Q-LV measurement to locate the area of latest activation. This is the standard of care method for pacing site optimisation.
Related Therapeutic Areas
Sponsors
Leads: University Hospital Birmingham