Exploring the Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients: an Open, Prospective, and Self-controlled Study

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

Dialysis patients have a higher incidence of cardiovascular events and require more effective measures to delay the progression of heart failure. Many studies have shown that dapagliflozin has cardioprotective effect, but most studies focus on non-dialysis patients with eGFR more than 20ml/min/1.73m2. However, the data on patients with eGFR less than 20ml/min/1.73m2 or dialysis patients, especially peritoneal dialysis patients, is less. Exploring the efficacy and safety of Dapagliflozin in improving heart failure in dialysis patients is of great clinical significance.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 70
Healthy Volunteers: f
View:

• 1.Age between 20 and 70 years old; 2.Maintenance dialysis for longer than 3 months; 3.Diagnosis with chronic heart failure, Left ventricular ejection fraction (LVEF)≤40% or NT-proBNP\>12000pg/ml; 4.The patient signs an informed consent form.

Locations
Other Locations
China
The People's Hospital of Gaozhou
RECRUITING
Maoming
Contact Information
Primary
Mingsheng Zhu
ms160@163.com
15016656405
Time Frame
Start Date: 2024-03-01
Estimated Completion Date: 2024-08-31
Participants
Target number of participants: 40
Treatments
Experimental: Self Control
Compare the heart function of dialysis patients before treatment and during the third and sixth months of treatment.
Related Therapeutic Areas
Sponsors
Leads: The People's Hospital of Gaozhou

This content was sourced from clinicaltrials.gov