Effects of Low-Sodium Substitute Salt on Death, Heart Failure Hospitalization, Heart Failure Emergency Department Visits, and Quality of Life in Patients With Heart Failure: A Multicenter, Double-Blind, Randomized Controlled Trial
This study aims to investigate whether using a low-sodium substitute salt can help improve outcomes for patients with heart failure. Specifically, it will examine if the low-sodium substitute salt can reduce death rates, hospital readmissions, and emergency visits, as well as improve the quality of life for these patients.
• Aged between 18 and 75 years;
• Hospitalized due to heart failure in the past year;
• NYHA functional class II-III;
• Echocardiographic evidence of LVEF \< 40% within the past 6 months;
• Receiving guideline-directed medical therapy for heart failure;
• Stable heart failure status, defined as heart failure stability for more than 4 weeks, with no increase in diuretic dose within the past 4 weeks;
• Having a primary caregiver and frequently dining together at home;
• Consuming commercially processed food no more than once a week;
• Providing written informed consent.