Acute Heart Failure - COngestion Repeated Evaluation (AHF-CORE). Evaluation répétée de la Congestion au Cours d'Une Hospitalisation Pour Insuffisance Cardiaque aigüe

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure, Biological, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The AHF-CORE study is a prospective, non-randomized, multicenter regional study. The main objective of the AHF-CORE study is to identify congestion markers (clinical, biological and ultrasound) at the beginning and at the end of hospitalization for acute heart failure that are more strongly associated with the risk of all cause death or rehospitalization for acute heart failure within 3 months of hospital discharge. Secondary objectives are: * Quantify the variations in congestion markers between the beginning and end of hospitalization for acute heart failure. * Assess the correlation between changes in congestion markers between the beginning and end of hospitalization. * Identify the congestion markers at the beginning of hospitalization that are most strongly associated with residual congestion at the end of hospitalization. * Identify the added value of ultrasound and biological markers of congestion in addition to clinical variables for the prediction of all-cause death or hospitalization for acute heart failure at 3 months after hospital discharge. * Identify the association of ultrasound and biologic congestion markers assessed at admission and final discharge with NYHA class at 3 months after hospital discharge

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients hospitalized for left-sided or global acute heart failure due to exacerbation of chronic heart failure within 72 hours of admission to hospital

• Patients over 18 years old

• Person affiliated to or beneficiary of a social security plan

• Person informed about study organization and having signed the informed consent

Locations
Other Locations
France
CHR Metz-Thionville - Hôpital de Mercy
RECRUITING
Metz
CHRU Nancy Hôpitaux de Brabois
RECRUITING
Vandœuvre-lès-nancy
Contact Information
Primary
Nicolas GIRERD, MD,PhD
n.girerd@chru-nancy.fr
+ 33 3 83 15 74 96
Time Frame
Start Date: 2018-02-13
Estimated Completion Date: 2026-02
Participants
Target number of participants: 80
Treatments
Experimental: Patients hospitalized for acute heart failure
One arm study.~Patients hospitalized for acute heart failure will undergo the following evaluations:~* Clinical examination centered on congestion~* Cardiopulmonary and peritoneal ultrasound~* Blood sample retrieved for biological assessment and biobanking~* Telephone interview
Related Therapeutic Areas
Sponsors
Leads: Central Hospital, Nancy, France

This content was sourced from clinicaltrials.gov

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