Heart Failure Clinical Trials

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Ted Rogers Understanding of Exacerbations in Heart Failure 2 (TRUE-HF2): Observational Study

Status: Recruiting
Location: See all (3) locations...
Study Type: Observational
SUMMARY

Heart Failure (HF) is a complex disease associated with the highest burden of cost to the healthcare system. The cardiopulmonary exercise test (CPET) is instrumental in determining the prognosis of patients with HF. This multicentre study will validate whether aggregate biometric data from the Apple Watch combined with demographic, cardiac, and biomarker testing can improve our ability to predict heart failure outcomes among a diverse outpatient HF population.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• broad age range (\> 18 years of age)

• NT-proBNP \> 400 or 1000 if in AF

• Within 3 months post discharge from HF hospitalization/ HF ED visit/ HF rapid clinic visit with intensification of diuretic therapy

• NYHA functional class I-IV, heart failure with reduced and preserved ejection fraction

• Literacy in English

• Patient provided informed consent

Locations
Other Locations
Canada
Southlake Health
NOT_YET_RECRUITING
Newmarket
200 Elizabeth Street
RECRUITING
Toronto
Sunnybrook Health Sciences Center
NOT_YET_RECRUITING
Toronto
Contact Information
Primary
Ryan Li, MASc
ryan.li@uhn.ca
6479669330
Backup
Ben Kim, PhD
ben.kim@uhn.ca
Time Frame
Start Date: 2026-06-16
Estimated Completion Date: 2029-09
Participants
Target number of participants: 360
Treatments
UHN Patients
Heart failure patients followed at UHN
Southlake Health Patients
Heart failure patients followed at Southlake Health
Sunnybrook Patients
Heart failure patients followed at Sunnybrook
Peterborough Regional Health Center Patients
Heart failure patients followed at Peterborough Regional Health Center
Related Therapeutic Areas
Sponsors
Collaborators: Canadian Institutes of Health Research (CIHR)
Leads: University Health Network, Toronto

This content was sourced from clinicaltrials.gov