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Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to evaluate whether dual-task inspiratory muscle training (IMT) is effective in improving cognitive and functional outcomes in adults with heart failure. It will also assess the effects of standard IMT and compare both approaches. The main questions it aims to answer are: * Does dual-task IMT improve cognitive function more than standard IMT or no intervention? * Does dual-task IMT improve respiratory function, inspiratory muscle strength, and exercise capacity? * What are the effects of dual-task IMT on symptoms such as dyspnea and fatigue, and on quality of life, anxiety, and depression? Dual-task IMT, standard IMT, and a control group (no additional intervention) will be compared to determine which approach is more effective in patients with heart failure (HF). Participants will: * Be randomly assigned to one of three groups: dual-task IMT, standard IMT, or control * Perform IMT training 5 days per week for 8 weeks (2 sessions per day, 15 minutes each) if assigned to an intervention group * Complete 1 supervised in-person session per week and 4 sessions via telerehabilitation if assigned to an intervention group * Undergo assessments before and after the 8-week intervention, including cognitive tests, respiratory function, exercise capacity, and symptom evaluations

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:

• Age ≥ 40 years

• Diagnosed with HF with reduced ejection fraction (HFrEF) according to the 2023 ESC HF Guidelines

• Classified as NYHA functional class I-III

• Clinically stable for at least 3 months and receiving stable pharmacological treatment

• Able to read and understand Turkish

• MoCA score ≥ 21

• Willingness to participate and provide written informed consent

Locations
Other Locations
Turkey
Istanbul University-Cerrahpaşa, Cardiology Institute
RECRUITING
Istanbul
Contact Information
Primary
Vildan Fidanoglu, PT, MSc
fzt.vildanbayraktaroglu@hotmail.com
212-924-24-44
Time Frame
Start Date: 2026-07-27
Estimated Completion Date: 2027-12
Participants
Target number of participants: 54
Treatments
Experimental: Dual-Task IMT
Participants will receive IMT combined with simultaneous cognitive tasks for 8 weeks (5 days/week, 2 sessions/day). One session per week will be supervised, and the remaining sessions will be performed via telerehabilitation. Training intensity will be set at 50% of MIP and adjusted weekly.
Experimental: Standard IMT
Participants will receive IMT alone for 8 weeks (5 days/week, 2 sessions/day). One session per week will be supervised, and the remaining sessions will be performed via telerehabilitation. Training intensity will be set at 50% of MIP and adjusted weekly.
No_intervention: Control (Usual Care)
Participants will not receive any additional intervention and will continue their usual medical care. Assessments will be performed at baseline and after 8 weeks.
Related Therapeutic Areas
Sponsors
Leads: Istanbul University - Cerrahpasa

This content was sourced from clinicaltrials.gov