Application of 18F-FDOPA PET and Magnetic Resonance Spectroscopy (MRS) in Research of the Association Between HCV Infection and Parkinson's Disease.
Status: Unknown
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The objective of this study is to investigate the evidence of dopaminergic toxicity causing by HCV infection using 18F-FDOPA PET and MRS as imaging biomarkers.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: t
View:
• Test Group
‣ Age：above 20 years old with HBV or HCV subjects.
⁃ Patient agrees to participate in the study and receive UPDRS, MMSE, BDI II, MRI and PET imaging.
• Control Group
‣ Age：above 20 years old without carriers of Hepatitis B and C (ex. fatty liver), and no known neurological (ex. stroke, Parkinson's disease and degenerative neuropathy, etc.) and mental illness.
⁃ Patient agrees to participate in the study and receive UPDRS, MMSE, BDI II, MRI and PET imaging.
Locations
Other Locations
Taiwan
National Taiwan Univeristy Hospital
RECRUITING
Taipei
Time Frame
Start Date: 2017-06-12
Completion Date: 2023-05-31
Participants
Target number of participants: 230
Treatments
Experimental: 18F-DOPA PET
PET/CT
Related Therapeutic Areas
Sponsors
Leads: National Taiwan University Hospital