Oral Health and Wilson's Disease: SOMAWI

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

Patients with Wilson disease have poorer dental and periodontal health and a have lower oral quality of life than control patients. Patients with a neurological form would also more frequently present limitations in the function of the masticatory apparatus. Systemic treatments for Wilson disease are associated with lesions of the oral mucosa. Analysis of copper level in saliva could testify to the effectiveness of copper depletion in treated patients The main objective is to compare the state of dental health between: patients with Wilson disease in the hepatic form and patients with the neurological form, and a population of controls.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Express consent to participate in the study

• Member of or beneficiary of a social security scheme

• For cases: Affected by Wilson's disease

• For controls: Benefiting from a first routine dental consultation with dental panoramic imaging, outside of an emergency context or treatment follow-up/maintenance

Locations
Other Locations
France
Hopital Charles Foix
ACTIVE_NOT_RECRUITING
Ivry-sur-seine
Hôpital Charles Foix
ACTIVE_NOT_RECRUITING
Ivry-sur-seine
Fondation Adolphe de Rothschild
RECRUITING
Paris
Contact Information
Primary
Amélie YAVCHITZ
ayavhitz@for.paris
01 48 03 64 54
Backup
Aurélia POUJOIS
apoujois@for.paris
01 48 30 66 56
Time Frame
Start Date: 2023-05-17
Estimated Completion Date: 2026-10
Participants
Target number of participants: 150
Treatments
Cases
patients with hepatic form of Wilson disease and those with neurological form
controls
control population consulting in routine dental with panoramic dental imaging, outside of an emergency context
Sponsors
Leads: Fondation Ophtalmologique Adolphe de Rothschild

This content was sourced from clinicaltrials.gov

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