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AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

Status: Recruiting
Location: See all (12) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The primary purpose of this clinical trial is to assess the safety and performance of the ECLIPSIUM device in securing mesh during ventral hernia repair. The study will evaluate whether ECLIPSIUM, a bioresorbable polymer-based fixation device, is effective in reducing the risk of hernia recurrence when compared with bioresorbable tacks. This information will support understanding of ECLIPSIUM's potential clinical benefits in ventral hernia repair.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 22
Healthy Volunteers: f
View:

• Patient is 22 years old or older.

• Patient is willing and able to provide a signed Patient Informed Consent Form.

• Patient has a single midline primary ventral, umbilical, or incisional hernia;

• a.Hernia Size is 1 -5 cm in diameter (to be confirmed intraoperatively).

• Patient is scheduled for a laparoscopic IPOM hernia repair.

• Hernia can be successfully repaired with a single polyester or polypropylene composite mesh with biodegradable coating with at least a 5 cm overlap of the mesh on all sides of the defect (to be confirmed intraoperatively).

• Female patients must:

‣ Have a negative urine pregnancy test within 3 days before surgery and agree to consistently use an effective method of contraception through completion of study participation.

‣ OR

⁃ Have reached menopause (no menses for 1 year). OR

⁃ Have undergone hysterectomy, bilateral oophorectomy, or tubal ligation.

• Patient is willing and able to follow the study instructions including completion of study procedures, assessments, and visits.

Locations
United States
California
VA Loma Linda
NOT_YET_RECRUITING
Loma Linda
Florida
University of Florida Health
NOT_YET_RECRUITING
Gainesville
Illinois
Northwestern University - Feinberg School of Medicine
RECRUITING
Chicago
Kentucky
University of Kentucky
NOT_YET_RECRUITING
Lexington
Michigan
University of Michigan Medical Center
NOT_YET_RECRUITING
Ann Arbor
North Carolina
Duke University
NOT_YET_RECRUITING
Durham
Novant Health New Hanover Regional Medical Center
RECRUITING
Wilmington
Nebraska
Creighton University
NOT_YET_RECRUITING
Omaha
Ohio
Cleveland Clinic Foundation
NOT_YET_RECRUITING
Cleveland
The Ohio State University Wexner Medical Center
RECRUITING
Columbus
Tennessee
University of Tennessee Medical Center
RECRUITING
Knoxville
Virginia
Tidewater Physicians Multi Specialty Group Hernia Center
RECRUITING
Newport News
Contact Information
Primary
Nikia Trinward
ntrinward@tissium.com
1-857-408-0709
Time Frame
Start Date: 2026-05-14
Estimated Completion Date: 2026-12
Participants
Target number of participants: 240
Treatments
Experimental: ECLIPSIUM System
The ECLIPSIUM System is intended for non-penetrating connection and fastening of prosthetic materials, such as composite meshes, to internal soft tissue during minimally invasive hernia repair procedures by coating the prosthetic material with the biodegradable implantable polymer and photoactivating it in situ with a TISSIUM curing light.
Active_comparator: Resorbable tacks (AbsorbaTack/SorbaFix)
Resorbable tacks are surgical fasteners used to secure a hernia mesh in place. Resorbable tacks are designed to be absorbed by the body over time, gradually losing strength as the tissue ingrowth into the mesh occurs and takes over the support function.
Related Therapeutic Areas
Sponsors
Leads: Tissium

This content was sourced from clinicaltrials.gov