• Male and female participants ≥ 18 years of age at the time of signing of the informed consent.

• Diagnosis of HS based on clinical history and physical examination for at least 6 months prior to the Baseline visit.

• Participants with moderate to severe HS defined as:

‣ A total of at least 5 AN count (abscesses and/or inflammatory nodules) AND

⁃ Inflammatory lesions should affect at least 2 distinct anatomic areas (e.g., left and right axillae)