DOSE DETERMINATION TRIAL: The Start/Persist Studies
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The proposed research will conduct the first dose-determination trial to find the optimal number of behavioral counseling sessions (dose) needed to achieve and sustain optimal HIV treatment adherence. The results of this study will determine how much intervention is needed for whom and at what cost to guide health policy and implementation of behavioral interventions designed to improve durable viral suppression.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Confirmed HIV positive
• Confirmed prescribed antiretroviral therapy
• Confirmed non-adherent to anti-retroviral therapy
Locations
United States
Connecticut
University of Connecticut
RECRUITING
Storrs
Georgia
University of Connecticut Field Site
RECRUITING
Atlanta
Contact Information
Primary
Seth Kalichman, PhD
seth.k@uconn.edu
860 208 3706
Time Frame
Start Date: 2020-09-01
Estimated Completion Date: 2026-11-30
Participants
Target number of participants: 400
Treatments
Active_comparator: Continuous Counseling
Receives up to 16 weekly behavioral counseling sessions over the phone to achieve optimal medication adherence. Counseling adjusts to patient needs and determines the dose to achieve optimal adherence / HIV suppression, in contrast to the fixed dose condition that does not adjust to patient response.
Active_comparator: Fixed Counseling
Receives up to five weekly behavioral counseling sessions over the phone focused on improving HIV medication adherence / viral suppression.
Related Therapeutic Areas
Sponsors
Leads: University of Connecticut
Collaborators: National Institute of Mental Health (NIMH)