Implementing an Evidence-Based, Multilevel Intervention to Promote HPV Vaccination Among HIV Positive Adults

Status: Recruiting
Location: See all (4) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

People living with HIV (PLWH) are 28 times more likely to be diagnosed with Human Papillomavirus (HPV) - associated anal cancer than the general population. The HPV vaccine is an effective and safe approach to prevent and reduce the risk of HPV-related disease among PLWH. HPV vaccine programs tailored and implemented in the HIV population are lagging for this high-risk group. The CDC's 4 Pillars Transformation Program is a multi-level, evidence-based intervention that has been successfully used to increase HPV vaccination in the general population and is ready to be tested in the high-risk HIV population, particularly PLWH in the rural South. This program offers providers and clinic staff evidence-based strategies to increase HPV vaccination uptake via training and educational resources. This study proposes to tailor and refine the 4 Pillars Program and conduct this project in three HIV clinics in Georgia.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:

• HIV positive

• 18-45 years of age

• Can read and speak English

• Capable of providing informed consent

• Has not previously received three series HPV vaccine

• No contraindications to receiving HPV vaccine (i.e. history of anaphylactic allergy to later, an immediate hypersensitivity to yeast, current moderate or severe acute illness, and/or are currently pregnant).

Locations
United States
Georgia
Albany Rural Model Clinic
RECRUITING
Albany
AID Atlanta
RECRUITING
Atlanta
Faebris
RECRUITING
Atlanta
AHF Lithonia
RECRUITING
Lithonia
Contact Information
Primary
Jessica Wells, PhD, RN
jholme3@emory.edu
404-727-0518
Backup
Robert Knott
rknott@emory.edu
404-727-3159
Time Frame
Start Date: 2023-05-22
Estimated Completion Date: 2027-06-01
Participants
Target number of participants: 365
Treatments
Experimental: 4 Pillars Program
Patients at study clinics who consent to have their HPV vaccination history verified with the Georgia Registry of Immunization Transactions and Services (GRITS).
No_intervention: Adjacent time-period Control Group
The background HPV update rate among PLWH will be obtained by using the electronic medical record (EMR) and GRITS to identify HPV vaccination uptake 18 months prior to the intervention. These data are collected retrospectively and no study participants are prospectively assigned to this study arm.
Sponsors
Collaborators: National Institute of Nursing Research (NINR)
Leads: Emory University

This content was sourced from clinicaltrials.gov