Impact of a Novel HIV Peer Navigation and Overdose Prevention Intervention on Engagement in the HIV Prevention and Treatment Cascade

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Through the proposed Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement (SCOPE) study, the investigators will design and evaluate an overdose prevention and HIV prevention study among people who use drugs (PWUD). Specifically, SCOPE will provide access to drug-checking services for PWUD to better understand the contents of the drug supply, in combination with PrEP for those who are HIV-, to both reduce overdose and HIV among PWUD in Baltimore City.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• 18 years or older,

• self-reports having used illicit stimulants or opioids at least once in the past 3 months,

• self-reports being HIV negative

• reports injection drug use in the past 6 months OR reports at least one of the following indicators of sexual HIV risk exposure in the past 6 months:

‣ Sexually Transmitted Infection (STI) diagnosis in the past 6 months

⁃ Condom-less vaginal or anal sex in the past 6 months

• Willing to provide a urine sample for urine drug screening of substances

• Willing to undergo rapid HIV testing

• Willing to undergo STI testing

Locations
United States
Maryland
Johns Hopkins School of Public Health
RECRUITING
Baltimore
Contact Information
Primary
Miles Morris, MPH
mmorr100@jhu.edu
410-502-4435
Backup
Susan G Sherman, PhD
ssherman@jhu.edu
410-614-3518
Time Frame
Start Date: 2023-07-28
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 500
Treatments
Other: SCOPE Cohort
A cohort of PWUD (N=500) living in Baltimore. We will follow-up with participants every 6 months (for 18 months) in five recruitment zones throughout Baltimore (n=125/zone). The four recruitment zones will overlap the intervention sites. There will be four study visits (baseline, 6 months, 12 months, 18 months) total for participants.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Baltimore City Health Department
Leads: Johns Hopkins Bloomberg School of Public Health

This content was sourced from clinicaltrials.gov