Effectiveness of Gut Microbiota-targeted Diatery Intervention in Preventing Atherosclerotic Cardiovascular Disease Among Older People Living With HIV

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to conduct a dietary intervention targeting HIV specific gut microbiota alterations for primary atherosclerotic cardiovascular disease (ASCVD) prevention and evaluate its effectiveness in preventing ASCVD among older people living with HIV (PLWH).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:

• HIV-infected patients diagnosed according to the diagnostic criteria of China AIDS diagnosis and treatment guidelines;

• Aged 40 years and above;

• at risk of CVD: having any two of those risk factors: dyslipidemia, DM or elevated blood glucose, smoking, hypertention or elevated blood pressure, metabolic syndrome,overweight/obesity; or PCE score\>5%,

• Those with a predicted survival time of \>1 year;

• No plans to leave the depth in the next 3 months;

• Voluntary participation in this study and signing the informed consent

Locations
Other Locations
China
The Third People's Hospital of Shenzhen
RECRUITING
Shenzhen
Contact Information
Primary
Junwen Yu, Dr
13320178333@163.com
13320178333
Time Frame
Start Date: 2024-08-20
Estimated Completion Date: 2025-05-20
Participants
Target number of participants: 110
Treatments
Experimental: intervention group
The intervention group will receive the gut microbiota targeted dietary intervention thrice weekly for 3 months, accompanied by bi-weekly healthy diet guidance for the same duration. The intervention will span three months, followed by a three-month follow up period
No_intervention: control group
The control group will continue routine follow-up and health education practices.
Related Therapeutic Areas
Sponsors
Leads: Fudan University

This content was sourced from clinicaltrials.gov