HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Phase 1
SUMMARY
The focus of this pilot will be on falls and neurocognitive symptoms, and the impact of alcohol, cannabis use, and medications on these outcomes. The rationale is that alcohol use at any level may interact with neurocognitively active medications, alcohol, and cannabis use leading to falls and impaired cognition.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: f
View:
• HIV+
• have visited a local VA site in within the past year
• had an AUDIT-C indicating current alcohol use
• taking 5 or more non-ART medications, including an NCAM (i.e., benzodiazepines, opioids, muscle relaxants, sleeping medication, and selective serotonin reuptake inhibitors)
Locations
United States
Connecticut
VA Connecticut Healthcare System
RECRUITING
West Haven
Contact Information
Primary
Amy C Justice, MD, PhD
amy.justice2@va.gov
203-932-5711
Time Frame
Start Date: 2025-01-15
Estimated Completion Date: 2025-12
Participants
Target number of participants: 100
Treatments
Experimental: Pharmacist lead intervention
Clinical pharmacists will be trained by a team with expertise in behavioral and HIV clinical care, and participate in a 10-hour training course with coaching sessions offered over the course of the study to ensure effective and consistent performance. Pharmacists will be guided by a manual designed to provide and walk them through the necessary skills to perform the pilot intervention easily and effectively. The manual will provide background information, study goals, and describe the critical components of the IMB-MI model and the HARP pilot interventions. An easy to follow, step-by-step approach to performing the intervention will be included. The study protocol to be followed by the clinical pharmacists will be included in the manual along with additional motivational and troubleshooting strategies. Systematic feedback regarding intervention fidelity will be provided by the Evaluation Team.
Related Therapeutic Areas
Sponsors
Leads: Yale University
Collaborators: National Institute on Alcohol Abuse and Alcoholism (NIAAA)