Tuberculosis Case Finding at the Completion of the CoVPN 3008 Clinical Trial: a Substudy to CoVPN 3008
Status: Recruiting
Location: See all (40) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
This substudy aims to identify cases of tuberculosis after the CoVPN 3008 clinical trial is completed.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:
• Enrollment into the CoVPN 3008 clinical trial.
• Able and willing to complete the informed consent process: Volunteer demonstrates an understanding of this substudy.
• Willingness to discuss TB status, undergo related testing/monitoring labs, and receive referrals for TB care.
Locations
Other Locations
Botswana
Gaborone CRS
RECRUITING
Gaborone
Kenya
Moi University Clinical Research Centre
RECRUITING
Eldoret
Kisumu Crs
RECRUITING
Kisumu
Kombewa Clinical Research Center
RECRUITING
Kisumu
Malawi
Blantyre CRS
RECRUITING
Blantyre
Malawi CRS
RECRUITING
Lilongwe
South Africa
Josha Resarch CRS
RECRUITING
Bloemfontein
Emavundleni CRS
RECRUITING
Cape Town
FAM-CRU (Family Clinical Research Unit)
RECRUITING
Cape Town
Groote Schuur HIV CRS
RECRUITING
Cape Town
Masiphumelele Clinical Research Site (MASI) CRS
RECRUITING
Cape Town
TASK Central
RECRUITING
Cape Town
Univeristy of Cape Town Lung CRS Institute
RECRUITING
Cape Town
CAPRISA eThekwini CRS
RECRUITING
Durban
Tongaat CRS
RECRUITING
Durban
Vulindlela CRS
RECRUITING
Durban
Synergy Biomed Research Institute
RECRUITING
East London
MeCRU CRS
RECRUITING
Ga-rankuwa
TASK Eden
RECRUITING
George
Isipingo CRS
RECRUITING
Isipingo
Clinical HIV Research Unit (CHRU)/ Helen Joseph CRS
RECRUITING
Johannesburg
Kliptown Soweto CRS
RECRUITING
Johannesburg
Newtown Clinical Research
RECRUITING
Johannesburg
Soweto - Bara CRS
RECRUITING
Johannesburg
Wits RHI Ward 21 CRS
RECRUITING
Johannesburg
Aurum Institute Klerksdorp CRS
RECRUITING
Klerksdorp
PHRU Matlosana CRS
RECRUITING
Klerksdorp
Qhakaza Mbokodo Research Clinic CRS
RECRUITING
Ladysmith
Nelson Mandela Academic Research Unit CRS
RECRUITING
Mthatha
PHOENIX Pharma (Pty) Ltd
RECRUITING
Port Elizabeth
Rustenburg CRS
RECRUITING
Rustenburg
Tembisa Clinic 4 CoVPN CRS
RECRUITING
Tembisa
Uganda
UVRI-IAVI HIV Vaccine Program LTD. CRS
RECRUITING
Entebbe
Baylor-Uganda CRS
RECRUITING
Kampala
Joint Clinical Research Centre
RECRUITING
Kampala
MU-JHU Research Collaboration CRS
RECRUITING
Kampala
Zambia
Cfhrz Crs
RECRUITING
Lusaka
Matero Reference Clinic CRS
RECRUITING
Lusaka
UNC Global Projects / Kamwala District Health Centre
RECRUITING
Lusaka
Zambia Emory HIV Research Project - Ndola CoVPN CRS
RECRUITING
Ndola
Contact Information
Primary
Clinical Trials Manager
csopher@fredhutch.org
206-667-2144
Backup
Protocol Team Leader
atapley@fredhutch.org
+1-260-667-1204
Time Frame
Start Date: 2024-10-21
Estimated Completion Date: 2025-10-05
Participants
Target number of participants: 6000
Treatments
Confirmed TB
Participants with confirmed TB will start treatment and have a follow-up visit soon after to check their TB symptoms again and collect blood samples. They will also have a second follow-up visit at week 26 to assess their treatment progress and TB status.
no TB (control)
Participants without TB will have a single follow-up visit to reassess TB symptoms and collect blood samples.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute of Allergy and Infectious Diseases (NIAID), Medical Research Council, South Africa
Leads: COVID-19 Prevention Network