Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR)
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to conduct a randomized controlled trial to evaluate the effectiveness of same-day HPV-based screen and treat among women living with HIV (WLH) in La Romana, Dominican Republic. With cervical cancer being a leading cause of cancer-related deaths in women living with HIV, and cervical cancer deaths being preventable through screening and early detection, this project seeks to identify factors associated with the successful implementation of the Screen, Triage, and Treat approach to inform future implementation and scale-up.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 25
Healthy Volunteers: t
View:
• 25 years of age;
• female sex assigned at birth (any gender identity);
• HIV-positive;
• women who have had cervical cancer precursor lesions which were removed more than 6 months ago; and
• understand Spanish
Locations
Other Locations
Dominican Republic
Clínica de Familia La Romana
RECRUITING
La Romana
Contact Information
Primary
Rebecca Schnall, PhD, MPH
rb897@columbia.edu
212-342-6886
Time Frame
Start Date:2026-02-23
Estimated Completion Date:2029-11-01
Participants
Target number of participants:600
Treatments
No_intervention: Standard of Care
Participants randomized to the standard of care group will receive standard examinations and management of screen positives (ablative therapy or colposcopy referral at a follow-up visit).
Experimental: Screen, Triage, and Treat
Participants randomized to the screen, triage, and treat group will be examined using the screen and treat approach (same day results and ablative therapy or colposcopy referral, if applicable).