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Reducing Mobility-associated Interruption in HIV Treatment in Malawi (REMIT): Pilot Trial to Assess Acceptability and Feasibility of a Mobility-specific Intervention Package

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this pilot clinical trial is to assess the feasibility and acceptability of an intervention package designed to reduce mobility-associated interruptions in HIV treatment in people living with HIV in Malawi who are initiating or returning to antiretroviral treatment (ART) after interruption. The main questions it aims to answer are: * Is the intervention acceptable to healthcare workers and ART clients? * Is the intervention feasible in the context of Malawi's health system, and what are the major operational challenges, resource requirements, and implementation barriers? In addition, researchers will compare HIV treatment outcomes (specifically ART retention rates) between intervention and control groups to establish a preliminary estimate of the intervention's efficacy. Participants will complete a survey on the day of enrollment and some participants will complete an in-depth interview and/or a survey after completion of the 6-month follow-up period. Facilities assigned to the intervention group will receive the full package of interventions (training on mobility-specific counseling for counsellors, access to a toll-free hotline for clients and healthcare workers, and training on multi-month dispensing for providers), while facilities assigned to the control group will provide standard of care.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 15
Healthy Volunteers: f
View:

• 15 years of age or older

• Living with HIV

• Attending ART clinic to initiate OR re-initiate care:

‣ Initiate: initiating ART for the first time, per self-report

⁃ Re-initiate: returning to care after missing a refill appointment by \>28 days

Locations
Other Locations
Malawi
Partners in Hope
RECRUITING
Lilongwe
Contact Information
Primary
Marguerite Thorp, MD, MPA/ID
mthorp@mednet.ucla.edu
(310) 267-5844
Backup
Kathryn Dovel, PhD, MPH
kdovel@mednet.ucla.edu
(310) 267-5844
Time Frame
Start Date: 2025-12-18
Estimated Completion Date: 2027-02
Participants
Target number of participants: 400
Treatments
Experimental: Intervention
Half of facilities will be randomized to intervention status and will receive the full package of interventions, including training on mobility-specific counseling for counsellors, access to a toll-free hotline for clients and healthcare workers, and training on multi-month dispensing for providers.
No_intervention: Control
Half of facilities will be randomized to control status and will administer standard of care with no additional interventions offered.
Related Therapeutic Areas
Sponsors
Leads: University of California, Los Angeles
Collaborators: National Institute of Mental Health (NIMH), Partners in Hope, Inc.

This content was sourced from clinicaltrials.gov

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