Human Papillomavirus Infection Clinical Trials

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Stories to Prevent (StoP) HPV Cancers: A Communication Intervention to Increase HPV Vaccination Among Diverse Populations.

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This randomized controlled trial (RCT) evaluates the association of a narrative communication intervention on human papillomavirus (HPV) vaccination rates among 9- to 12-year-olds. The intervention is a brief video from local cancer survivors narrating their stories with an HPV-related cancer diagnosis and recommending the HPV vaccine for cancer prevention. RCT participants will be the parents (n=200) of children ages 9-12 who have not initiated HPV vaccination. Participants will be randomized (1:1) to our intervention or control (placebo video) one week before their child's next primary care visit. Our primary outcome is HPV vaccine initiation (first dose of the HPV vaccine series) among children ages 9-12 at the time of the wellness visit. The study also explores the effect of narratives on theory-based mediators of HPV vaccination, including parents' cognitive (e.g., risk perception) and emotional reactions (e.g., hope, anticipated regret).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Parent/guardian of a 9-12 year old receiving primary care at a Penn State Health clinic

• Their child has not previously received or initiated the HPV vaccine

• Is able to read and understand spoken English or Spanish

• Has a valid email address and access to a mobile phone, table, desktop or laptop computer to engage in the intervention

Locations
United States
Pennsylvania
Penn State Health
RECRUITING
Hershey
Contact Information
Primary
William A Calo, PhD
wcalo@pennstatehealth.psu.edu
717-531-3535
Time Frame
Start Date: 2025-11-18
Estimated Completion Date: 2027-03-31
Participants
Target number of participants: 200
Treatments
Experimental: Cancer survivor narrative video
Parents randomly assigned to this arm will receive the video intervention using their personal devices around two weeks before their child's wellness visit. The video will be approximately 4 minutes in length with three parts: (1) Cancer experience, (2) Vaccine recommendation, and (3) Closing message.
Placebo_comparator: Placebo video
Parents randomly assigned to this arm will receive the placebo video using their personal devices around two weeks before their child's wellness visit. The placebo video is about healthy eating tips for families with children. The video will be approximately 4 minutes in length.
Related Therapeutic Areas
Sponsors
Leads: Milton S. Hershey Medical Center

This content was sourced from clinicaltrials.gov