TweenVax: A Comprehensive Practice-, Provider-, and Parent/Patient-Level Intervention to Improve Adolescent HPV Vaccination

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This clinical trial compares the effect of a vaccine promotional intervention, TweenVax, to standard of care vaccination promotion practices on rates of human papillomavirus (HPV) vaccination in adolescents. HPV vaccination has been identified as a priority for cancer prevention and control by the Cancer Moonshot Blue Ribbon Panel, which estimated that increasing HPV vaccination rates can prevent 400,000 HPV-related cancers in the next 5-10 years. The goal is for HPV vaccinations to be completed by the age of 13. It has been estimated that only about 16% of adolescents were fully up to date with HPV vaccines by age 13. Strong and consistent provider recommendations have been shown to play an important role in the uptake of vaccines. In addition, education and information received by parents may improve the strength of recommendations by providers. The TweenVax intervention includes practice, provider, parent and patient level education to teach best practices, help with vaccine messaging, and give correct and easy to understand information to parents. Providing practice, provider and parent level access to TweenVax may be more effective than current vaccine promotion practices in improving HPV vaccination rates in adolescents.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 9
Healthy Volunteers: t
View:

• PRACTICE-LEVEL: Must be community based primary care providers (pediatrics or family practice)

• PRACTICE-LEVEL: Are willing to be part of the study

• PRACTICE-LEVEL: Have sufficient patient population to support 51 adolescents aged 9-12 years over approximately a 9-month period

• PRACTICE-LEVEL: Utilize an electronic medical records system and/or report to the state Immunization Information System (IIS)

• CHILD/ADOLESCENT: Aged 9-12 years

• CHILD/ADOLESCENT: Seeking care from an enrolled practice during the study period

• CHILD/ADOLESCENT: Have not received any doses of HPV vaccine by the time of their first visit during the study period

Locations
United States
Georgia
Emory University Hospital/Winship Cancer Institute
RECRUITING
Atlanta
Contact Information
Primary
Robert Bednarczyk, PhD
rbednar@emory.edu
404-727-9713
Time Frame
Start Date: 2025-05-02
Estimated Completion Date: 2028-03-06
Participants
Target number of participants: 1836
Treatments
Experimental: Arm I (TweenVax, practice, provider, parent, patient level)
Practices receive all TweenVax components and trainings related to the practice, provider and staff, parent and adolescent-level intervention. Parents receive access to the TweenVax application and receive TweenVax vaccination information using the provided tablet during clinical encounters on study.
Experimental: Arm II (practice and provider)
Practices receive components and trainings related to the practice and provider-level intervention on study.
Active_comparator: Arm III (control)
Practices continue to offer standard of care adolescent vaccination promotion practices to adolescent patients on study.
Related Therapeutic Areas
Sponsors
Leads: Emory University
Collaborators: National Cancer Institute (NCI)

This content was sourced from clinicaltrials.gov