Monitoring of the Influence of Approved PH-therapies RV-PA Coupling

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to learn about the acute (days) changes in right ventricular functions caused by initiation of pharmacological therapies in patients with precapillary pulmonary hypertension. The main question it aims to answer is: • Course of afterload and intrinsic contractility throughout the hospital stay Participants will be equipped with a device for continuous monitoring and recording of the right ventricular pressure signal.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Initial diagnosis of PH (treatment-naive incident PH) of the Nice classifications 1 (PAH), 3 (PH related to lung diseases/hypoxia), and 4 (CTEPH), or known PH under ongoing vasoreactive therapy

• No contraindications for right heart catheterization, conductance catheterization, or CorLog implantation

• Written consent from the patient or their legal guardian

Locations
Other Locations
Germany
Department of Internal Medicine, Justus Liebig University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL)
RECRUITING
Giessen
Contact Information
Primary
Khodr Tello, MD
khodr.tello@innere.med.uni-giessen.de
+49 (0)641 985 56022
Time Frame
Start Date: 2023-02-13
Estimated Completion Date: 2026-02-13
Participants
Target number of participants: 100
Related Therapeutic Areas
Sponsors
Leads: University of Giessen

This content was sourced from clinicaltrials.gov

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