Comparison of Exercise Capacity, Muscle Oxygenation and Aortic Stiffness in Patients With a History of Mitral Valve Intervention for Mitral Stenosis With Healthy Subjects

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Heart valve diseases are the most common cause of mortality and morbidity after coronary artery disease, hypertension, and heart failure. In patients with mitral stenosis, the narrowed valve restricts blood flow, causing symptoms such as shortness of breath, fatigue, exertional dyspnea, orthopnea, and paroxysmal nocturnal dyspnea. These patients may experience decreased exercise capacity and physical activity levels, deterioration in quality of life, and deterioration in respiratory function. When reviewing the literature, we see that the study groups evaluating these factors are generally not homogeneous, and most studies conducted in patients with mitral stenosis evaluate patients who have undergone percutaneous mitral balloon valvuloplasty.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:

⁃ Patients;

• Between the ages of 18-80

• Patients who have undergone mitral valve intervention due to mitral stenosis

• At least 3 months have passed since the intervention

⁃ Healthy controls;

• Between the ages of 18 and 80

• Agreeing to participate voluntarily in the study

Locations
Other Locations
Turkey
Gazi University Faculty of Health Sciences Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit
RECRUITING
Ankara
Contact Information
Primary
Meral BOŞNAK GÜÇLÜ, Prof. Dr.
meralbosnak@gazi.edu.tr
+90(312)2162647
Backup
Ebrar TÜLÜMENOĞLU, Pt
25854401007@gazi.edu.tr
Time Frame
Start Date: 2025-01-13
Estimated Completion Date: 2026-07
Participants
Target number of participants: 40
Treatments
Patients group
This group includes patients who have undergone mitral stenosis intervention for mitral stenosis. Patients exercise capacity using Cardiopulmonary Exercise Test (CPET), muscle oxygenation with a near-infrared spectroscopy device, respiratory functions with a spirometer, respiratory muscle strength with a mouth pressure measurement device, respiratory muscle endurance with an incremental threshold loading respiratory muscle endurance test, aortic stiffness with an arteriograph, physical activity level with a multisensor physical activity monitor and quality of life with the SF-36 Short Form will be evaluated.
Healthy Controls Group
Healthy controls will be evaluated for exercise capacity with the Cardiopulmonary Exercise Test (CPET), muscle oxygenation with a near-infrared spectroscopy device, respiratory functions with a spirometer, respiratory muscle strength with a mouth pressure measurement device, respiratory muscle endurance with an incremental threshold loading respiratory muscle endurance test, aortic stiffness with an arteriograph, physical activity level with a multisensor physical activity monitor, and quality of life with the SF-36 Short Form.
Sponsors
Leads: Gazi University

This content was sourced from clinicaltrials.gov