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CONNECT-HTN Trial - Coaching and Navigation by CHWs Through Telehealth for High-risk Hypertension

Status: Recruiting
Location: See all (4) locations...
Intervention Type: Behavioral, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The investigators propose an intervention that leverages the success of Community Healthcare Workers (CHWs) and telehealth to connect patients with severe hypertension from Emergency Department (ED) to primary care resources and to coach them to adopt evidence-based, practical lifestyle solutions relevant to urban living. The investigators have proposed this intervention as Coaching and Navigation by Community Health Workers (CHWs) through Telehealth for High-risk Hypertension: CONNECT-HTN intervention. The investigators hypothesize that participants receiving the CONNECT-HTN intervention will have a lower likelihood of experiencing a major cardiac event compared with those referred to clinic-based care.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Eligible patients

• Must be over the age of 18 years

• Have an ED triage SBP \> 180 and/or DBP \> 110, with a repeat similar reading ≥30 minutes after triage

• May have received treatment for elevated BP, but must have no evidence of end-organ damage (acute stroke, acute coronary syndrome, acute kidney injury, or papilledema)

• May be admitted for deranged BP only with no complications, or may be stable for discharge per treating emergency physician

• Include referrals from the clinic to the ED with SBP/DBP values in the inclusion range

• Can provide informed consent. Intervention is accessible to individuals of all literacy levels

• Can receive phone calls and in-person visits. Smartphone ownership not required (intervention compatible with analog phones)

Locations
Other Locations
Pakistan
Aga Khan University Hospital (AKUH)
RECRUITING
Karachi
Dow University of Health Sciences, Ojha Campus (DUHS)
RECRUITING
Karachi
Jinnah Postgraduate Medical Center (JPMC)
RECRUITING
Karachi
Sindh Institute of Emergency and Health Sciences (SIEHS)
RECRUITING
Karachi
Contact Information
Primary
Junaid A Razzak, MD PhD FACEP
jur9123@med.cornell.edu
+1 4437229239
Backup
Sheza Hassan, MD MSc
shh4019@med.cornell.edu
+1 9296213558
Time Frame
Start Date: 2026-03-16
Estimated Completion Date: 2029-08
Participants
Target number of participants: 3620
Treatments
Active_comparator: Referral arm
In the referral arm, patients with hypertension will receive a digital BP monitor (an Omron device), a brief teaching session on its proper use, and an emergency medical services number for any medical concerns. A small outcomes team will visit their household within 3 months of their discharge from the Emergency Department (ED) to review their readings and ask a few more questions about their health. This outcome team will visit every 6 months for a total of five home visits to monitor their health.
Experimental: T-CHW arm
In the T-CHW arm, patients with hypertension will receive a digital BP monitor (an Omron device) and a brief teaching session on its proper use. They will also be connected with a Community Healthcare Worker (CHW) via a telephone number. The CHW will call them to ask about their health and counsel them on diet and exercise to support good blood pressure control. The CHW will call them every month at a mutually convenient time for up to 36 months.~A small outcomes team will visit their household within 3 months of their discharge from the ED to review their readings and ask a few more questions about their health. This outcome team will visit every 6 months for a total of five home visits to monitor their health.
Related Therapeutic Areas
Sponsors
Leads: Weill Medical College of Cornell University
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)

This content was sourced from clinicaltrials.gov