Hypertension Clinical Trials

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A Low-Cost, Scalable Treatment Strategy for Improving Hypertension Control in Low and Middle-Income Settings: Formative Phase (Aim 1)

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

This study includes a survey of primary healthcare facilities in Nigeria and Sri Lanka. It will aim to assess the availability and readiness of hypertension care in primary healthcare facilities, and feasibility to conduct a future randomised controlled trial. This study also includes a survey of patients with high blood pressure who will be recruited from primary care in Sri Lanka and Nigeria. Its aim is to understand the characteristics of patients with hypertension, hypertension management and control, including use of pharmacological interventions and lifestyle management. Patients will have their blood pressure, height and weight measured. They will also be asked about their age, sex/gender, socio-economic status, medical history, and health behaviours and lifestyle. Additionally, this study includes focus group discussions and in-depth interviews with adults with high blood pressure and their carers; healthcare providers (community health workers, nurses, and doctors or physicians); clinic administrators; and policymakers. The discussions and interviews will aim to explore experiences, practices, and views on hypertension care and the new treatment strategies. Topics will cover experiences of current high blood pressure care; service availability, accessibility, and affordability; healthcare staff training and how well they follow medical guidelines for helping patients with high blood pressure; what works well and what are the problems with helping patients with high blood pressure; experiences of patients who need help with their high blood pressure; and how well new ways of helping people with high blood pressure are received.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

⁃ \- primary care facility must be located in the Federal Capital Territory in Nigeria, and in the Gampaha District in Sri Lanka

• adult (age ≥18 years)

• hypertensive (defined as prior documented diagnosis of hypertension, or current use of BP-lowering drugs for hypertension, or SBP ≥140 mmHg, and/or DBP ≥90 mmHg measured on two separate occasions)

Locations
Other Locations
Nigeria
University of Abuja
RECRUITING
Abuja
Sri Lanka
RemediumOne
RECRUITING
Colombo
Time Frame
Start Date: 2026-04-01
Estimated Completion Date: 2026-08-31
Participants
Target number of participants: 1357
Treatments
Cross-Sectional Facility Survey (SARA)
Service Availability and Readiness Assessment of primary care facilities in Sri Lanka and Nigeria
Cross-Sectional Patient Survey
Cross-sectional survey of adult patients with hypertension recruited from primary care facilities screened as part of Cross-Sectional Patient Survey
Qualitative Focus Groups Discussions and In-Depth Interviews
Focus group discussions and in-depth interviews with patients and healthcare providers/policymakers will explore experiences and perceptions of hypertension care, including acceptability of current and proposed management strategies.
Related Therapeutic Areas
Sponsors
Collaborators: University of Kelaniya, The George Institute for Global Health, Australia, The University of New South Wales, University of Abuja, The George Institute, RemediumOne
Leads: Imperial College London

This content was sourced from clinicaltrials.gov