Exercise Performance on Ambient Air vs. Commonly Prescribed Nasal Low Flow Oxygen Therapy in Patients With Exercise Induced Desaturation Due to Pulmonary Disease
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The investigators aim to study the effect of liquid oxygen therapy (4l/min, nasal) )in Swiss residents with pulmonary vascular diseases (PVD) defined as pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• \- Minimum 18 years of age
• Written informed consent
• Patients with diagnosed pulmonary arterial hypertension (PAH), distal chronic thromboembolic pulmonary hypertension (CTEPH), chronic obstructive pulmonary disease (COPD) with emphysema, COPD without emphysema, or interstitial lung disease
• Former desaturation under exercise defined as SpO2-decrease \>3%
• Treated with a stable drug therapy (with no changes for at least 14 days prior to screening)
Locations
Other Locations
Switzerland
University Hospital Zurich
RECRUITING
Zurich
Contact Information
Primary
Silvia Ulrich, Prof. Dr. med.
silvia.ulrich@usz.ch
+41442552220
Backup
Mona Lichtblau, PD. Dr. med.
mona.lichtblau@usz.ch
+41442552220
Time Frame
Start Date: 2026-08-01
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 40
Treatments
Experimental: Ambient air
Patient will be assessed at University Hospital Zurich
Active_comparator: Liquid oxygen therapy via nasal canula
Supplemental Liquid Oxygen Therapy (LOX) at approximately 4l/min will be provided via nasal canula from a small oxygen tank at University Hospital Zurich to perform clinical assessments.
Related Therapeutic Areas
Sponsors
Leads: Silvia Ulrich Somaini