• Fulfillment of the inclusion criteria for hypothermia treatment according to the AWMF guideline

• Severe acidosis (pH ≤7.0 or a base deficit ≥16 mmol/l) in umbilical cord blood or a blood sample from the first hour of life, and

• clinical signs of moderate or severe encephalopathy (severity grade 2 or 3 according to Sarnat \& Sarnat), and

• postnatal age ≤6h, and

• gestational age ≥36 weeks' gestation

• Consent of the parents/legal guardians

• Time 1 (before the start of hypothermia treatment)

‣ Informing the parents/legal guardians present on site despite an emotionally stressful situation with high individual benefit for the patient

⁃ If only one parent is present and able to provide information, their consent is sufficient - the second parent is informed repeatedly when they regain the ability to provide information

⁃ Information adapted to the emergency situation, addressing the personal situation and comprehensible presentation of the plan

• Time 2 (during hypothermia treatment)

⁃ -\>Offer of a further informative discussion/repeated explanation with the parents/legal representatives before the second measurement in order to answer any questions that may have arisen

• Suitable acoustic window

• Availability of the qualified examiner